Protein Details: Aquaporin-2
Protein ID
ICDB_Pro_0265
Protein Name
Aquaporin-2
Gene Name
AQP2
Organism
Erinaceus europaeus (Western European hedgehog)
Length
109 amino acids
AlphaFoldDB
AF-O77722-F1-model_v4.pdb
Function
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water; thereby permitting water to move in the direction of an osmotic gradient.
Sequence
SIAFSRAVFTEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLAIGTLVQMLGHISGAHINPAVTVACLVGCHISFLRAAFYVAAQLLGAVAGAALLHEVTPPSIRG
PDB Structures
Ligand Binding
Binding Site
Disease
Location
DOI ID
10.1006/mpev.1998.0517